RA is a chronic, inflammatory disease that requires regular measurement of disease activity to prevent progressive joint damage.1
Structural damage can continue even when symptoms appear under control.1,2
No single biomarker has been proven reliable for predicting radiographic progression.3,4Watch video
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Single biomarkers, such as CRP and ESR, are incomplete measures of RA disease activity.5
CRP and ESR levels were low in the majority of 9,135 patients with active RA (CDAI >2.8) studied from the CORRONA registry.5
CDAI = clinical disease activity index; CORRONA = Consortium of Rheumatology Researchers of North America; CRP = C-reactive protein; ESR = erythrocyte sedimentation rate; RA = rheumatoid arthritis